AI is being infused into new and classic software everywhere and making it into production, but there’s little consideration given to testing the resulting AI-infused applications (AIIAs). This report is a galvanizing call to application development and delivery (AD&D) professionals in enterprise organizations to apply testing disciplines and practices to AIIAs. It is also a mandate to address the testing of AI-based autonomous software, which will open up a new world for software testers and their tools. This is the first in a two-part series of documents on testing AI-infused software. Read the second in the series, “It’s Time To Get Really Serious About Testing Your AI: Part Two,” next.