The inside-out approach of engineers focused on technology for its own sake must stop: Your business cares about outcomes and holistic services, not server, storage, and network technologies. For too long, I&O has aligned with silos of technology expertise, resulting in complexity, poor communication, low satisfaction, and wasted money. To deliver better business results over the next decade, Forrester advocates that you take a "workload-centric" approach: Design your IT infrastructure on what matters most — your workloads — not the other way around. This report outlines the landscape of workload-centric IT infrastructure and explains how to apply this approach across your people, process, and technology to optimize IT infrastructure sourcing, deployment, staffing, and budgeting.