Pharmaceutical firms are changing their business operating models in response to market globalization, consolidation, and regulatory pressures. These changes require a stronger partnership between business and IT. Business capability maps provide a framework for capturing key characteristics of a firm's business model and core functions — characteristics that you then can use to assess business needs, understand IT costs, and align investments with strategic priorities. This report explains how pharmaceutical firms can use capability maps to illustrate changes in the operating model and to support the business-IT partnership.