Agentic AI introduces autonomy and emergent behaviors that traditional security models cannot contain. CISOs face a dual mandate: Accelerate AI adoption and prevent privilege escalation, cascading failures, and regulatory exposure. Forrester’s AEGIS Framework includes six domains of guardrails that, when embedded into AI agent activation, transform exposure into resilience. Security leaders can use this report to adapt the AEGIS AI-Agent-On-A-Page template to enforce governance, identity, and least agency from design through deployment.