Soaring chronic disease prevalence, an aging population, and the COVID-19 pandemic have depleted and exhausted the American nursing workforce and catalyzed the largest nursing shortage in recent history. The burden on clinicians and the entire healthcare ecosystem is at an all-time high. The consequences of RN staffing shortages are imminently destructive, but mitigating RN burnout isn’t as complex as it seems. This report identifies the talent management strategies that healthcare organizations (HCOs) and clinical executives must implement to build and maintain a resilient nursing workforce and develop a steadfast talent management plan for the future.