Leaders — and especially technology executives — face a new, career-defining challenge: making generative AI (genAI) work for employees. Giving an employee an AI copilot isn’t enough. Making copilots successful requires collaboration across disciplines and includes a new kind of player — domain experts to ensure that genAI models make intellectual, not just automation, contributions. Follow the principles of human-centered design, process automation, and domain intelligence to build and successfully deploy AI copilots that work.