B2B leaders must integrate AI into their supplier-operated digital commerce capabilities to stay ahead in a competitive landscape. A stepwise approach that starts with piloting select AI use cases and gradually expanding to a broader range of capabilities is essential. By leveraging AI to enhance digital commerce experiences, suppliers will increase engagement and customer value, enabling leaders to create an advantage over slower-moving competitors. This report provides an overview of the top AI use cases for B2B digital commerce, including those which enable customer-centric innovation and improve organizational efficiency and operational success.