Healthcare organizations (HCOs) have long leaned on cloud platforms for genomic sequencing, temperature- and time-specific delivery, access to modern data center technologies, and software-as-a-service (SaaS) platforms that they consume through their independent software vendors (ISVs). In recent years, cloud has been a key tool in enabling organizations to become more adaptable, capable, resilient, and innovative. As the pandemic stabilizes, the healthcare sector is stepping back to organize, secure, and operationalize as it explores the next wave of innovation. This report informs healthcare cloud leaders on the trends and challenges to expect in 2023.