Organizations with strong alignment among the sales, product, and marketing functions can deliver 19% faster revenue growth and 15% higher profitability. The heads of marketing, sales, and product must also strive for optimal internal alignment across their own various teams and between the corporate and regional entities that need to operate together. Too often, however, they fail to acknowledge that external dynamics or internal shifts create the need to adjust corporate and regional relationships. We introduce four key states of corporate/regional alignment and offer specific guidance that helps marketing leaders optimize this alignment across their teams.