Businesses with sizable mainframe estates are connecting these systems to cloud and distributed workloads and often modernizing elements of these workloads at the same time. This is driving mainframe DevOps adoption so that these initiatives can achieve the product innovation velocity needed to address evolving customer demands. Accelerating mainframe DevOps adoption means knowing where and how to start the process. This report helps frame the key challenges in adopting mainframe DevOps and builds a path to addressing those challenges to create a sustainable mainframe DevOps practice.