Transforming your company’s culture for digital disruption is one of the key challenges digital leaders face today. Sharon Cooper, BMJ Publishing Group’s (BMJ) chief digital officer (CDO), knew that an “organizational change plan where everyone watches a video and you rearrange your desks wouldn’t work.” BMJ needed a more fundamental culture shift to become a truly digital business. This case study examines the key steps BMJ took to change their culture — measures that can be applied by CIOs, CTOs, and CDOs across different industries.